Best Hot Sauce in Buffalo, NY: 4 Makers, Ranked
Joey G's Sauce Company bottles its sauces in North Tonawanda. The recipe dates to 1976, and Ed's 5-Alarm Reaper Sauce sells at $15.00, with heat from Carolina Reaper Peppers. Nick's Spider Venom Hot Sauce sells 5 oz bottles for $8.00. Buffalo Tom's Gourmet Hot Sauce has been in the marketplace since 2002 and runs between medium and hot.

The ranking

Illustrative image from published details; not a photograph of the premises or packaging. Joey G's Sauce Company
The company bottles its sauces by hand in small batches in North Tonawanda, working from a 1976 family recipe. Ed's 5-Alarm Reaper Sauce is priced at $15.00 and built on Carolina Reaper Peppers. Its heat is listed as Crazy Hot with a Buffalo backbone. Southwestern Buffalo Sauce, Medium lists at $10.00. Retail stock includes Buffalo Gift Emporium in Tonawanda and Williamsville.

Illustrative image from published details; not a photograph of the premises or packaging. Nick's Spider Venom Hot Sauce sells 5 oz bottles at $8.00 and 16 oz bottles at $13.00. The heat ladder runs Single Bite, Double Bite, Triple Bite and Death. The sauce began as a home experiment when the couple could not find the heat and depth they wanted. Retailers include The Nickel Plate on Clinton St. in Buffalo, and the phone line is (716) 863-8646.

Illustrative image from published details; not a photograph of the premises or packaging. Buffalo Tom's Gourmet Hot Sauce
Buffalo Tom's Gourmet Hot Sauce entered the marketplace in 2002 and is sold in bottles to retailers and by the gallon to restaurants and pizzerias. The sauce sits between medium and hot. It was picked as a regional specialty item at the Taste NY Welcome Center in Grand Island for August 2019. The label now carries 2 extra ounces.

Illustrative image from published details; not a photograph of the premises or packaging. Buffalo Sauce Co.
Buffalo Sauce Co. makes its sauces locally in Buffalo, with flavors running from mild up to Carolina Reaper hot. Bottles are listed at $3.00 each, including Rajun Cajun, The Reaper and Italian Parmesan. The company lists a Buffalo phone line at 716-473-9859.
FAQ
What style of hot sauce is Buffalo known for?
Area restaurants made the standard sauce by mixing hot sauce and melted butter. Joey G's sells its Signature line in Mild, Medium, Hot, Extra Hot, Oogly Boogly and Habanero Ooogly Boogly heat levels.
What are the cheapest hot sauce bottles in Buffalo?
Buffalo Sauce Co. lists its sauces at $3.00 a bottle. Nick's Spider Venom sells 5 oz bottles at $8.00.
Which Buffalo hot sauce makers use Reaper?
Ed's 5-Alarm Reaper Sauce at Joey G's is built on Carolina Reaper Peppers. Buffalo Sauce Co. takes its flavor range up to Carolina Reaper hot.
Which Buffalo hot sauce makers ship online?
Nick's Spider Venom quotes shipping costs by location and takes direct orders for addresses outside its local delivery range.